BPC-157 — Research Guide
BPC-157 is a synthetic pentadecapeptide fragment derived from Body Protection Compound, a protein originally isolated from gastric juice. It is one of the most widely cited research peptides in tissue-signaling literature, frequently studied alongside TB-500 in cell-migration, angiogenesis, and extracellular-matrix research.
Research Use Only — Not FDA-Approved
Orion compounds are for in-vitro laboratory research only and are not for human consumption.
Product
BPC-157 10mg
Purity
99.2%
CAS
137525-51-0
Single
$24.99
10-pack/vial
$18.74
Chemistry & identity
BPC-157 (CAS 137525-51-0, MW 1419.53 g/mol) has the 15-amino-acid sequence GEPPPGKPADDAGLV. Solid-phase synthesis; per-batch HPLC purity (≥ 99.2% on current lots) and MS confirmation of identity against theoretical mass.
Research applications
- Angiogenesis and nitric-oxide pathway modulation studies
- Cell-migration and cytoprotective signaling research
- Extracellular-matrix remodeling assays
- Comparative tissue-signaling vs TB-500
- Growth-factor expression in cell culture models
- Tendon, gastric mucosa, soft tissue, articular, and dermal research models
Stability & storage
Lyophilized BPC-157 is stable at −20°C. After reconstitution, refrigerated storage (2–8°C) is supported by published in-solution stability data. Avoid repeated freeze-thaw cycles in solution.
Published half-life range
5h midpoint (lit. 4h – 6h)
Source: Sikiric et al., Curr Pharm Des, multiple reviews 2010-2020. See the half-life calculator for predicted in-solution decay over time.
Direct comparisons
Related research guides
Wolverine Stack — Research Guide
The Wolverine Stack is a pre-mixed lyophilized formulation of BPC-157 + TB-500 (5mg of each per vial). It is commonly used in tissue-signaling research because the two compounds act through complementary mechanisms — BPC-157 via nitric-oxide and growth-factor pathways, TB-500 via actin sequestration and cell migration.
Glow Stack — Research Guide
The Glow Stack is a multi-peptide lyophilized blend centered on GHK-Cu, formulated for dermatological-signaling and dermal-fibroblast research. It is used in copper-peptide combination studies and dermal extracellular-matrix research designs.
FAQ
BPC-157 vs TB-500 — when do researchers use which?
They target different mechanisms. BPC-157 modulates nitric-oxide signaling, growth factor expression, and ECM dynamics. TB-500 (a Thymosin β4 fragment) primarily acts via actin sequestration and cell migration. They're often co-administered in research (Wolverine Stack) precisely because the mechanisms are complementary.
Is the spray version different from the lyophilized?
Orion ships lyophilized BPC-157 (10mg vial). Solution and nasal-spray formulations from other vendors are pre-reconstituted and pre-formulated; the lyophilized form gives the researcher full control over reconstitution concentration and storage.
Where does Orion ship BPC-157?
BPC-157 cannot ship to Texas under HB 1817 compounded-peptide restrictions. See the restricted substances policy for the full list.
Is this for human use?
No. In-vitro research use only.