Orion

Restricted Substances Policy

Last updated: April 2026

1. Scope

Certain research compounds offered by Orion cannot be shipped to certain U.S. states because of state-level statutes regulating research chemicals, peptides, cosmetics, or pharmaceutical-grade materials. This list reflects our current shipping policy. It is not a legal opinion on the status of any compound, and it is not exhaustive.

2. Current Restrictions

Melanotan I
California · New York · Texas · Florida · Massachusetts

Synthetic α-MSH analogue. Melanocortin-receptor research compound. Shipment restricted in listed states under state cosmetic and pharmaceutical statutes.

Melanotan II
California · New York · Texas · Florida · Massachusetts

Cyclic melanocortin-receptor agonist. Shipment restricted in listed states under state cosmetic and pharmaceutical statutes.

PT-141 (Bremelanotide)
California · New York · Texas · Florida · Massachusetts

Melanocortin receptor agonist. Shipment restricted in listed states under state pharmaceutical and cosmetic statutes.

Retatrutide
California · New York · Texas · Louisiana · Mississippi

GLP-1/GIP/glucagon receptor research compound. Shipment restricted in listed states under state pharmacy compounding statutes covering GLP-1-class preparations.

Tirzepatide
California · New York · Texas · Louisiana · Mississippi

Dual GIP/GLP-1 receptor research compound. Shipment restricted in listed states under state pharmacy compounding statutes covering GLP-1-class preparations.

Semaglutide
California · New York · Texas · Louisiana · Mississippi

GLP-1 receptor research compound. Shipment restricted in listed states under state pharmacy compounding statutes covering GLP-1-class preparations.

Cagrilintide
California · New York · Texas · Louisiana · Mississippi

Amylin-analogue research compound. Shipment restricted in listed states under state pharmacy compounding statutes covering compounded peptide preparations.

BPC-157
Texas

Compounded peptide preparation. Shipment restricted under Texas HB 1817 (compounded peptide preparations).

TB-500
Texas

Compounded peptide preparation. Shipment restricted under Texas HB 1817 (compounded peptide preparations).

3. Automatic Enforcement

Our checkout automatically blocks the purchase of restricted compounds when the shipping address is in a restricted state. Attempts to bypass this enforcement — including through misrepresentation of the shipping address — are a material breach of our Terms of Service and will result in cancellation of the order.

4. Buyer Compliance Obligation

Buyers are solely responsible for determining whether the purchase, possession, handling, and use of any product complies with all applicable federal, state, and local laws in their jurisdiction. The absence of a compound from this list does not mean that it is legal in any particular jurisdiction for any particular use. Orion makes no representation as to the legality of its products in any specific location.

5. Updates

This list is reviewed periodically and may be updated without notice. If you have questions about the availability of a specific compound in a specific jurisdiction, contact our support team before placing an order.