Melanotan II — Research Guide
Melanotan II is a cyclic 7-amino-acid synthetic peptide and a non-selective melanocortin-receptor agonist. It is widely used in melanocortin-receptor signaling research and is one of the most-cited reference agonists in MC1R / MC3R / MC4R / MC5R selectivity studies.
Research Use Only — Not FDA-Approved
Orion compounds are for in-vitro laboratory research only and are not for human consumption.
Product
Melanotan II 10mg
Purity
98.7%
CAS
121062-08-6
Single
$29.99
10-pack/vial
$22.49
Chemistry & identity
Melanotan II (CAS 121062-08-6, MW 1024.17 g/mol) is a cyclic peptide — the cyclization confers conformational rigidity and metabolic stability vs linear α-MSH. Per-batch HPLC + MS verification.
Research applications
- Non-selective melanocortin receptor agonism (MC1R-MC5R)
- Cyclic-peptide conformational-restriction studies
- Receptor-selectivity profiling vs Melanotan I (NDP-α-MSH)
- Pigmentation and melanocortin signaling pathway research
- Cyclic-peptide proteolytic stability characterization
Stability & storage
Lyophilized Melanotan II is stable at −20°C. The cyclic structure confers strong protease resistance and supports refrigerated storage post-reconstitution.
Published half-life range
51 min midpoint (lit. 0.5h – 1.2h)
Source: Dorr et al., Life Sci 1996. See the half-life calculator for predicted in-solution decay over time.
FAQ
Where can Orion ship Melanotan II?
Melanotan II is restricted from delivery to CA, NY, TX, FL, and MA under various state cosmetic and pharmaceutical statutes. See the restricted substances policy for details.
Melanotan II vs Melanotan I (NDP-α-MSH)?
Melanotan I (NDP-α-MSH) is the linear 13-amino-acid α-MSH analogue. Melanotan II is the shorter cyclic 7-amino-acid analogue. The cyclization gives Melanotan II distinct receptor-selectivity and stability properties.
What purity does Orion ship?
≥ 98.7% by reversed-phase HPLC, batch-specific value on the COA.
Is this for human use?
No. In-vitro research use only.