Orion
§ Research GuideNeuropeptide Research

Selank — Research Guide

Selank is a synthetic heptapeptide analogue of tuftsin developed in Russia as a neuropeptide research compound. It is studied in anxiolytic-pathway, cytokine-modulation, and neuropeptide-receptor research, and is one of the most-cited compounds in modern tuftsin-derivative literature.

Research Use Only — Not FDA-Approved

Orion compounds are for in-vitro laboratory research only and are not for human consumption.

Product

Selank 10mg

Purity

99.3%

CAS

129954-34-3

Single

$34.99

10-pack/vial

$26.24

View product

Chemistry & identity

Selank (CAS 129954-34-3, MW 751.87 g/mol) has the sequence TKPRPGP — Thr-Lys-Pro-Arg-Pro-Gly-Pro. The C-terminal Pro-Gly-Pro extension distinguishes it from tuftsin (TKPR) and confers extended in-solution stability.

Research applications

  • Tuftsin-analogue receptor binding studies
  • GABAergic neurotransmission modulation in cell-line and tissue assays
  • Cytokine and immune-modulation peptide research
  • Intranasal-route bioavailability research models
  • Neuropeptide stability and protease-resistance characterization

Stability & storage

Lyophilized Selank is stable at −20°C. The proline residues at the C-terminus contribute to enzymatic stability — Selank is notably more protease-resistant in solution than parent tuftsin.

Published half-life range

9 min midpoint (lit. 0.08h – 0.3h)

Source: Kozlovskaya et al., Eksp Klin Farmakol 2003 (free peptide; intranasal absorption differs). See the half-life calculator for predicted in-solution decay over time.

Direct comparisons

Related research guides

FAQ

Selank vs Adamax — which is more potent in research?

They target different mechanisms. Selank is a tuftsin analogue acting on neuropeptide-receptor pathways. Adamax is a modified Semax analogue with an adamantane moiety. Selection depends on the assay system. See the Adamax vs Selank comparison page for direct specs.

What's the half-life of free Selank in plasma?

Very short (minutes) in published plasma studies of the free peptide. Intranasal-route bioavailability is the focus of much of the published research because of this short systemic half-life.

What purity does Orion ship?

≥ 99.3% by reversed-phase HPLC, batch-specific value on the COA.

Is this for human use?

No. In-vitro research use only.

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