NAD+ — Research Guide
NAD+ (Nicotinamide Adenine Dinucleotide) is a fundamental coenzyme in cellular energy metabolism. Unlike most compounds in our catalog, NAD+ is a small molecule (not a peptide). It is one of the most-cited research substrates in mitochondrial-function, sirtuin-pathway, and cellular-bioenergetics literature.
Research Use Only — Not FDA-Approved
Orion compounds are for in-vitro laboratory research only and are not for human consumption.
Product
NAD+ 100mg
Purity
99.1%
CAS
53-84-9
Single
$17.99
10-pack/vial
$13.49
Chemistry & identity
NAD+ (CAS 53-84-9, MW 663.43 g/mol) is a small-molecule coenzyme — a dinucleotide composed of nicotinamide and adenine linked through phosphate groups via two ribose sugars. Per-batch HPLC + MS verification.
Research applications
- Sirtuin-pathway substrate-availability research
- Mitochondrial respiratory-chain substrate studies
- PARP-family enzyme substrate research
- Cellular redox-state and NAD+/NADH ratio assays
- Comparative studies with precursors (NMN, NR)
Stability & storage
Lyophilized NAD+ is stable at −20°C protected from moisture and light. Aqueous solutions are sensitive to pH extremes and oxidation; published research uses neutral-pH buffers and immediate refrigeration.
Published half-life range
12 min midpoint (lit. 0.1h – 0.5h)
Source: Cantó et al., Cell Metab 2012; tissue half-life longer than plasma. See the half-life calculator for predicted in-solution decay over time.
Direct comparisons
Related research guides
FAQ
NAD+ vs NMN — which is the research substrate?
NAD+ is the active coenzyme. NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside) are biosynthetic precursors. Orion stocks NAD+ directly.
Why is the per-mg cost so low?
NAD+ is a small molecule, not a synthetic peptide. The synthesis cost and per-mg price scale very differently. At $17.99 for 100mg, the $/mg cost is one of the lowest in our catalog.
What's the in-solution stability?
Plasma half-life of free NAD+ is short (minutes); tissue half-life is longer. See published cell-biology literature and the half-life calculator.
Is this for human use?
No. In-vitro research use only.